Interaction Survival

Survival Interaction

Interaction Survival is a program to calculate either estimates of sample size or power for tests of interaction. Exponential distributions are assumed and are specified as a ratio of the hazard ratio for the treatment effect in stratum 1 to the hazard ratio for the treatment effect in stratum 2. The program allows for unequal sample size allocation in the four cells defined by the two treatment groups and two strata. An exponentially distributed competing risk is also permitted.

User Input
Program Output

Sample size
Power
1 Sided
2 Sided
Alpha
Accrual
Follow
Comp Risk

Cell Freq Treat1/Strat1
Cell Freq Treat1/Strat2
Cell Freq Treat2/Strat1
Cell Freq Treat2/Strat2
Hazard Rate Treat1/Strat1
Hazard Rate Treat1/Strat2
Haz Ratio T1/T2 Strat1
Haz Ratio T1/T2 Strat2

Power
Sample size