Binomial Interaction

Interaction Binomial is a program to calculate either estimates of sample size or power for interaction tests. Alternatives are specified as a ratio of the odds ratio of the treatment effect in stratum 1 vs the odds ratio of the treatment effect in stratum 2. The program allows for unequal sample size allocation in the four cells defined by the two treatment groups and two strata.

User Input
Program Output

Sample size
Power
1 Sided
2 Sided
Alpha

Cell Freq Treat1/Strat1
Cell Freq Treat1/Strat2
Cell Freq Treat2/Strat1
Cell Freq Treat2/Strat2
Event Prob Treat1/Strat1
Event Prob Treat1/Strat2
Odds Ratio T1/T2 in Strat1
Odds Ratio T1/T2 in Strat2

Power
Sample size