Two Arm Survival - Interim Stopping

Futility Monitoring on a standard 2 arm randomized Phase II study. Specify Standard Design for two arms. Specify interim analysis in terms of accrual time, + additional follow. Calculate tests and HR1 rule at interim analysis. Conduct test at complete analysis.

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User Input
Program Output

Select Parameters

Type Input



Number of Simulations
Total Sample Size
Proportion in Standard Group
Hazard Rate, Std.
Null Hazard Ratio
Alternative Hazard Ratio
Years of Accrual
Years of Follow-up
Proportion of Events
Proportion of Accrual at Interim
Years of Follow-up at Interim
Alpha
Alpha at Interim Analysis